DBCO-Lys(m-PEG4)-Val-Ala-PAB dbco-dap-m-PEG4 93 SMILES ClCCOCCOCCOCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

93 SMILES ClCCOCCOCCOCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

512 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Small molecule induced polymerization of BCL6 facilitates SIAH1 mediated degradation

Product Name Thalidomide-C4-amine HCl Synonyms Thalidomide-4'-C4-amine HCl CAS Number n/a Related CAS Molecular Formula C17H20ClN3O4 Molecular Weight 365

DBCO-Lys(m-PEG4)-Val-Ala-PAB dbco-dap-m-PEG4 93 SMILES ClCCOCCOCCOCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,