Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8) BCN Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS

Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C76H104FN9O25 Molecular Weight 1562

418 SMILES OCCCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

and bioconjugation

Product Name: Lenalidomide-5'-CO-C1-amine HCl Synonyms: CAS Number: n/a Molecular Formula: C15H17ClN4O4 Molecular Weight: 352

Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8) BCN Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker