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1038/nature18621
It induces degradation of SALL4 (ZF2)
1799711-25-3 (TFA salt) Molecular Formula C19H23ClN4O6 Molecular Weight 438
Product Name Phthalimidinoglutarimide-C6-OH Synonyms Phthalimidinoglutarimide-4'-C6-OH CAS Number n/a Related CAS Molecular Formula C19H24N2O4 Molecular Weight 344
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-PNP Size:100mg 1038/nature18621SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating
