Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP protac precursor 33 SMILES OCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

33 SMILES OCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

349 Purity (HPLC) >= 95% Solubility DMSO

Product Name CDg18 Synonyms CAS Number N/A Related CAS Molecular Formula C33H48N2O4 Molecular Weight 536

Product Name 1-[2-(piperazin-1-yl)ethyl]piperazine Synonyms CAS Number 19479-83-5 Related CAS Molecular Formula C10H22N4 Molecular Weight 198

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP protac precursor 33 SMILES OCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation