TMP-POM 7c Halotag 587 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCN2C(=O)C=CC2=O)=[N+](C)C)=C1

587 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCN2C(=O)C=CC2=O)=[N+](C)C)=C1

5-FAM is the purified single isomer of carboxyfluorescein

Product Name NRX-1532 Synonyms CAS Number n/a Related CAS Molecular Formula C16H11F3N4O2 Molecular Weight 348

With excitation maximum at 547 nm

TMP-POM 7c Halotag 587 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCN2C(=O)C=CC2=O)=[N+](C)C)=C1The TMP tag is based on the tight binding between trimethoprim (TMP), a synthetic antibiotic, and Escherichia coli dihydrofolate reductase (eDHFR), a small enzyme with a high affinity for TMP. By fusing eDHFR to a protein of interest and introducing TMP linked to a probesuch as a fluorescent dye, biotin, or other functional groupresearchers can selectively label and study proteins in their native cellular environment. TMP POM 7c is a trimethoprim