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Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg dCeMM1 is a glue degrader

SKU 87944582257
4.1
EUR495.00 EUR526.00

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Description

dCeMM1 is a glue degrader of RBM39 that functions by re-directing the activity of the CRL4DCAF15 ligase

Product Name Thalidomide-O-acetamido-PEG2-propargyl Synonyms Thalidomide-4'-O-acetamido-PEG2-propargyl CAS Number n/a Related CAS Molecular Formula C22H23N3O8 Molecular Weight 457

11 (TFA Salt) SMILES: NCCNC(=O)C1=CC=C2C(=C1)C(=O)OC21C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2

Product Name: Cy3 alkyne monosulfo Synonyms: Cy3 alkyne

Azide-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:1mg dCeMM1 is a glue degraderSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase

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