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Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:10mg 823 Purity (HPLC) >= 95%

SKU 84544838435
4.9
USD445.00 USD484.00

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Description

823 Purity (HPLC) >= 95% Solubility DMSO

Product Name GSK1790627 Synonyms CAS Number 871701-87-0 Related CAS Molecular Formula C24H23FIN5O4 Molecular Weight 591

Product Name Thalidomide-O-acetamido-PEG2-C2-amine HCl Synonyms Thalidomide-4'-O-acetamido-PEG2-C2-amine HCl CAS Number 2376990-30-4 Related CAS 1957235-74-3 (free base)

Product Name tert-butyl 4-(piperazin-1-yl)butanoate Synonyms CAS Number n/a Related CAS Molecular Formula C12H24N2O2 Molecular Weight 228

Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:10mg 823 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP

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