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A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins
Product Name DOTA-C6-propanamido-maleimide (TFA salt) Synonyms CAS Number n/a Related CAS Molecular Formula C37H51F12N7O18 Molecular Weight 1109
Endogenous tagging enabled the visualization and the selective depletion of a SNAP-clathrin light chain fusion protein using SNAP-PROTACs
986 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCN=[N+]=[N-])CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae A near-infrared fluorophore for live-cellSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
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