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Product Name 5-(Methoxy-d3)-2-methylaniline Synonyms CAS Number n/a Related CAS Molecular Formula C8H11NO Molecular Weight 140
DOTA bifucational chelator containing an amine-reactive NHS group
which reacts with benzylguanine (BG)or chloropyrimidine (CP) derivatives
It is preferred for some complicated biological applications where reproducibility is more critical since the minor positional difference between 5-ROX and 6-ROX might significantly affect some biological properties of the underlying conjugates
Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE ca Product Name 5-(Methoxy-d3)-2-methylaniline Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl
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