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Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg Product Name DOTA-C6-azide Synonyms CAS

SKU 8086469358
4.3
USD495.00 USD518.00

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Description

Product Name DOTA-C6-azide Synonyms CAS Number n/a Related CAS Molecular Formula C22H40N8O7 Molecular Weight 528

NCCOCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

and Hoechst Janelia Fluor 646 (Hoechst-JF646)

96 SMILES ClCCOCCOCCOCCOCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg Product Name DOTA-C6-azide Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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