Azide-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg BODIPY FL VH032 is a

BODIPY FL VH032 is a high-affinity fluorescent probe for the von Hippel–Lindau (VHL) protein

972 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

The taselisib-induced degradation of mutant p110a protein is ubiquitin-mediated and proteasome-dependent

179 Purity (HPLC) >= 95% Solubility DMSO

Azide-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg BODIPY FL VH032 is aSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing