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VHL-SNAP2-5C propargyl as the acetylation masks the

SKU 7930476706
4.0
USD195.00 USD245.00

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Description

as the acetylation masks the hydroxyl groups critical for fluorescein’s fluorescence

Product Name Phthalimidinoglutarimide-5'-C5-OH Synonyms CAS Number 2229715-00-6  Related CAS Molecular Formula C18H22N2O4 Molecular Weight 330

Compared with regular HaloTag Ligand

89 SMILES ClCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

VHL-SNAP2-5C propargyl as the acetylation masks theVHL SNAP2 5C is a SNAP PROteolysis TArgeting Chimera (SNAP PROTAC), which recruit the VHL or CRBN ubiquitin E3 ligases to induce the degradation of SNAP fusion proteins. Endogenous tagging enabled the visualization and the selective depletion of a SNAP clathrin light chain fusion protein using SNAP PROTACs. The addition of PROTACs to the SNAP tag reagent toolbox facilitates the comprehensive analysis of protein function with a single gene tagging

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