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Structural basis for the action of the drug trametinib at KSR-bound MEK
Product Name CC-90009 Synonyms Eragidomide CAS Number 1860875-51-9 Related CAS Molecular Formula C22H18ClF2N3O4 Molecular Weight 461
It has the spectral properties identical to those of other 6-ROX conjugates
Product Name Pomalidomide-CO-C3-azide Synonyms Pomalidomide-4'-CO-C3-azide CAS Number 2227423-22-3 Related CAS Molecular Formula C17H16N6O5 Molecular Weight 384
dCeMM2 ptotac ligand Structural basis for the actiondCeMM2 (Compound 2) is a glue degrader. dCeMM2 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12 cyclin K with a CRL4B ligase complex. Product Name dCeMM2 Synonyms CAS Number 296771 07 8 Related CAS Molecular Formula C16H11ClN6OS Molecular Weight 370. 82 SMILES ClC1=CC=C(NC(=O)CSC2=NN=C3C(NC4=CC=CC=C34)=N2)N=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO, DMF Shipping Conditions Room
