Pay in 4 interest-free payments of $111.25 Learn more
Ships within 48 hours · Estimated delivery Aug 24 - Aug 29
BCN reacts efficiently with azides to form stable 1
S)-AHPC-CO-C5-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C32H50Cl2N6O4S Molecular Weight 685
148 Purity (HPLC) >= 95% Solubility DMSO
linking two molecules covalently
Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan acid-acid BCN reacts efficiently with azidesSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
