Val-Cit-PAB(m-PEG8) carboxylic acid 74 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(O)=O)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC):

74 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(O)=O)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

86 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name: Texas Red alkyne Synonyms: Sulforhodamine 101 alkyne CAS Number: N/A Molecular Formula: C68H66N6O12S4 Molecular Weight: 643

63 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Val-Cit-PAB(m-PEG8) carboxylic acid 74 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(O)=O)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC):SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned