Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan protac O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(=CC=C12)N1CCNCC1 Purity (HPLC) 95% Shipping

O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(=CC=C12)N1CCNCC1 Purity (HPLC) 95% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only

Development of BODIPY FL Thalidomide As a High-Affinity Fluorescent Probe for Cereblon in a Time-Resolved Fluorescence Resonance Energy Transfer Assay

emission maximum = 525 nm

Sulforhodamine 101 is particularly well suited for excitation by the 568 nm spectral line of the Ar – Kr mixed gas laser commonly used in many confocal laser-scanning microscopes or the 594 nm spectral line of the orange He-Ne laser

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan protac O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(=CC=C12)N1CCNCC1 Purity (HPLC) 95% ShippingSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by