NRX-252114 Size:5mg 384 SMILES OCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)

384 SMILES OCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

dCeMM1 is a glue degrader of RBM39 that functions by re-directing the activity of the CRL4DCAF15 ligase

It is a good glutamate transglutaminase substrate and a useful building block for small fluorescent molecules

thus has excellent cell permeability

NRX-252114 Size:5mg 384 SMILES OCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)NRX 252114 is an enhancer of the interaction between beta catenin and beta TrCP. NRX 252114 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta catenin by the 26S proteasome. Product Name NRX 252114 Synonyms CAS Number 2763260 39 3 Related CAS Molecular Formula C22H12Cl2F3N3O2S Molecular Weight 510. 31 SMILES FC(F)(F)C1=CC(SC2=C(Cl)C=CC=C2Cl)=C(C(=O)N2CC3=CC=CC(C#N)=C3C2)C(=O)N1 Purity (HPLC) >= 95%