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Product Name Thalidomide-O-C4-OH Synonyms Thalidomide-4'-O-C4-OH CAS Number 2636072-82-5 Related CAS Molecular Formula C17H18N2O6 Molecular Weight 346
S)-AHPC-acetamido-O-PEG4-C1-acid Synonyms CAS Number 2172820-13-0 Related CAS Molecular Formula C34H50N4O11S Molecular Weight 722
It reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)
821 Purity (HPLC) >= 95% Solubility DMSO
DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-aldehyde Product Name Thalidomide-O-C4-OH Synonyms Thalidomide-4'-O-C4-OHSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
