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Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan deuterium-labeled-aldehyde Product Name Thalidomide-O-acetamido-PEG4-OH Synonyms Thalidomide-4'-O-acetamido-PEG4-OH

SKU 64858947727
4.7
USD445.00 USD474.00

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Ships within 48 hours · Estimated delivery Aug 23 - Aug 28

Description

Product Name Thalidomide-O-acetamido-PEG4-OH Synonyms Thalidomide-4'-O-acetamido-PEG4-OH CAS Number n/a Related CAS Molecular Formula C23H29N3O10 Molecular Weight 507

Product Name Indisulam Synonyms CAS Number 165668-41-7 Related CAS Molecular Formula C14H12ClN3O4S2 Molecular Weight 385

Product Name Pomalidomide-CO-C4-azide Synonyms Pomalidomide-4'-CO-C4-azide CAS Number n/a Related CAS Molecular Formula C18H18N6O5 Molecular Weight 398

Product Name 2-Chloro-1-(methoxy-d3)-3-nitrobenzene Synonyms CAS Number n/a Related CAS Molecular Formula C7H6ClNO3 Molecular Weight 190

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan deuterium-labeled-aldehyde Product Name Thalidomide-O-acetamido-PEG4-OH Synonyms Thalidomide-4'-O-acetamido-PEG4-OHSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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