Phthalimidinoglutarimide-5'-propargyl-PEG1-OH azide Gillingham

Gillingham

064 SMILES [H]C(=O)C1=CC=C(Br)C(OC([2H])([2H])[2H])=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

It reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)

Product Name Thalidomide-O-acetamido-C3-azide Synonyms Thalidomide-4'-O-acetamido-C3-azide CAS Number n/a Related CAS Molecular Formula C18H18N6O6 Molecular Weight 414

Phthalimidinoglutarimide-5'-propargyl-PEG1-OH azide GillinghamDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Phthalimidinoglutarimide 5' propargyl PEG1 OH Synonyms CAS Number 2619512 41 1 Related CAS Molecular Formula C18H18N2O5 Molecular Weight 342. 351 SMILES OCCOCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95%