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Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP propargyl CDCF) can passively diffuse into

SKU 53446337545
4.5
USD345.00 USD370.00

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Description

CDCF) can passively diffuse into cells and is colorless and nonfluorescent until the acetate groups are cleaved by intracellular esterases to yield the fluorescent fluorophore

Product Name DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C90H115FN10O25 Molecular Weight 1755

P1h is a HaloTag ligand incorporating the fluorogenic AggFluor P1 dye

DOTA bifucational chelator containing an alkyne group

Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP propargyl CDCF) can passively diffuse intoSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as

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