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MC-Val-Cit-PAB(m-PEG8)-MMAE carboxylic acid BG-SS-SulfoCy5 is a membrane-impermeable probe

SKU 51608437591
4.0
EUR495.00 EUR530.00

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Description

BG-SS-SulfoCy5 is a membrane-impermeable probe that covalently binds to the SNAP-tag

CA-TMR has been used for tracking protein localization

265 SMILES NC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

94 SMILES ClCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

MC-Val-Cit-PAB(m-PEG8)-MMAE carboxylic acid BG-SS-SulfoCy5 is a membrane-impermeable probeSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

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