Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:5mg enabling kinetic measurements

enabling kinetic measurements

Thalidomide is an immunomodulatory compound with diverse biological activities

Sci Transl Med 2021

Product Name: 5(6)-ROX Synonyms: 5-(and 6)-Carboxy-X-rhodamine CAS Number: 198978-94-5 Molecular Formula: C33H30N2O5 Molecular Weight: 534

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:5mg enabling kinetic measurementsSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous