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Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8) ggfg S)-AHPC-CO-PEG5-C2-amine HCl Synonyms CAS Number

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Description

S)-AHPC-CO-PEG5-C2-amine HCl Synonyms CAS Number 2375432-97-4 Related CAS Molecular Formula C35H56ClN5O9S Molecular Weight 758

Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C88H142N14O26 Molecular Weight 1812

06 SMILES ClCCOCCOCCOCCOCCOCCOCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

336 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8) ggfg S)-AHPC-CO-PEG5-C2-amine HCl Synonyms CAS NumberSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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