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the introduction of the charged sulfonate group minimally altered the excitation and emission profiles compared to the non-sulfonated TMR-d12 (HTL:
It induces degradation of SALL4 (ZF2)
BG-CPY is a SNAP-tag substrate containg CPY dye
Product Name: 5(6)-TMARA C2 maleimide Synonyms: Tetramethylrhodamine-5(and 6) C2 maleimide CAS Number: N/A Molecular Formula: C31H28N4O6 Molecular Weight: 552
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4) tamra the introduction of the chargedSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX
