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DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg Achieving In Vivo Target Depletion

SKU 46477874547
4.8
EUR445.00 EUR490.00

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Description

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders

6-FAM PEG3 azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry

Product Name Thalidomide-O-acetamido-PEG2-C2-amine HCl Synonyms Thalidomide-4'-O-acetamido-PEG2-C2-amine HCl CAS Number 2376990-30-4 Related CAS 1957235-74-3 (free base)

Product Name: 5(6)-ROX Synonyms: 5-(and 6)-Carboxy-X-rhodamine CAS Number: 198978-94-5 Molecular Formula: C33H30N2O5 Molecular Weight: 534

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg Achieving In Vivo Target DepletionSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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