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Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan macrophage Product Name Pomalidomide-PEG5-C2-acid Synonyms Pomalidomide-4'-PEG5-C2-acid

SKU 42719982963
4.6
USD445.00 USD476.00

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Ships within 48 hours · Estimated delivery Aug 16 - Aug 21

Description

Product Name Pomalidomide-PEG5-C2-acid Synonyms Pomalidomide-4'-PEG5-C2-acid CAS Number 2139348-63-1 Related CAS Molecular Formula C26H35N3O11 Molecular Weight 565

Product Name CP-CPY Synonyms SNAP2-CPY CAS Number Related CAS Molecular Formula C40H39ClN6O4 Molecular Weight 703

Product Name Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C55H85N7O20 Molecular Weight 1164

Product Name CC-92480 Synonyms Mezigdomide CAS Number 2259648-80-9 Related CAS Molecular Formula C32H30FN5O4 Molecular Weight 567

Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan macrophage Product Name Pomalidomide-PEG5-C2-acid Synonyms Pomalidomide-4'-PEG5-C2-acidSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU

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