tert-butyl 4-{2-[4-(2-aminoethyl)piperazin-1-yl]ethyl}piperazine-1-carboxylate click GW5074 reduces mHTT levels through

GW5074 reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)

89 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Texas Red PEG3 azide Synonyms Sulforhodamine 101 PEG3 azide CAS Number N/A Related CAS Molecular Formula C39H46N6O9S2 Molecular Weight 806

NCCOCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC): 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

tert-butyl 4-{2-[4-(2-aminoethyl)piperazin-1-yl]ethyl}piperazine-1-carboxylate click GW5074 reduces mHTT levels throughNitrogen Heterocycle Based Linker (NHBL). Binfunctional amine amine linker. Product Name tert butyl 4 {2 [4 (2 aminoethyl)piperazin 1 yl]ethyl}piperazine 1 carboxylate Synonyms CAS Number n a Related CAS Molecular Formula C17H35N5O2 Molecular Weight 341. 5 SMILES CC(C)(C)OC(=O)N1CCN(CCN2CCN(CCN)CC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory