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Fmoc-Val-Cit-PAB sir SHP099 is a highly potent

SKU 3958030211
4.7
EUR90.00 EUR124.00

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Description

SHP099 is a highly potent (IC50 = 0

Product Name Lenalidomide-CO-C3-Br Synonyms Lenalidomide-4'-CO-C3-Br CAS Number 2089207-02-1 Related CAS Molecular Formula C17H18BrN3O4 Molecular Weight 408

Product Name Thalidomide-O-acetamido-C5-amine HCl Synonyms Thalidomide-4'-O-acetamido-C5-amine HCl CAS Number 2716130-28-6 Related CAS 2360527-40-6 (free base)

416 SMILES CC(C)(C)OC(=O)CN1CCN(CC1)C1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Fmoc-Val-Cit-PAB sir SHP099 is a highly potentFmoc Val Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug, and the Fmoc protecting group can be removed to enable further functionalization or conjugation. Product Name Fmoc Val Cit PAB Synonyms Fmoc VC PAB OH CAS Number 159858 22 7

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