DOTA-tris(t-Bu)ester-C2-maleimide amine-acid has enhanced potency in PIK3CA

has enhanced potency in PIK3CA mutant models through a unique mechanism of action

599 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCOCCOCCOCCOCCOCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Pomalidomide-CO-C2-alkyne Synonyms Pomalidomide-4'-CO-C2-alkyne CAS Number 2408797-68-0 Related CAS Molecular Formula C18H15N3O5 Molecular Weight 353

Product Name Trametinib Synonyms CAS Number 871700-17-3 Related CAS Molecular Formula C26H23FIN5O4 Molecular Weight 615

DOTA-tris(t-Bu)ester-C2-maleimide amine-acid has enhanced potency in PIK3CADOTA bifucational chelator containing a thiol reactive maleimide group, an alkyl linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA tris(t Bu)ester C2 maleimide Synonyms CAS Number 1613382 10 7 Related CAS Molecular Formula