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Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:25mg S)-AHPC-acetamido-O-PEG4-C2-amine HCl Synonyms CAS Number

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Description

S)-AHPC-acetamido-O-PEG4-C2-amine HCl Synonyms CAS Number 2377275-23-3 Related CAS 2377275-22-2 (free base) Molecular Formula C34H54ClN5O9S Molecular Weight 744

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Structural basis for the action of the drug trametinib at KSR-bound MEK

757 Purity (HPLC) >= 95% Physical Appearance Yellow solid Optical Properties Abs/Em Maxima: 444/525 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:25mg S)-AHPC-acetamido-O-PEG4-C2-amine HCl Synonyms CAS NumberSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para

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