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PC-6 Size:100nmol 36 SMILES CC(C)(C)OC(=O)NCCN1CCN(CC(O)=O)CC1 Purity (HPLC)

SKU 34646243757
4.8
EUR245.00 EUR294.00

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Ships within 48 hours · Estimated delivery Aug 16 - Aug 21

Description

36 SMILES CC(C)(C)OC(=O)NCCN1CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Cy3 carboxylic acid

Signal Transduction and Targeted Therapy

01 SMILES Cl

PC-6 Size:100nmol 36 SMILES CC(C)(C)OC(=O)NCCN1CCN(CC(O)=O)CC1 Purity (HPLC)PC 6 is a specially designed fluorescent probe for detecting SARM1 activity, built by conjugating a styryl donor group to a pyridine acceptor to form a donoracceptor system. It functions through SARM1s base exchange reaction, where PC 6 is converted into a positively charged product (PAD6) upon incorporation into NAD, leading to strong intramolecular charge transfer and a large fluorescence shift (from ~430 nm to ~520 nm). Among a series of related

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