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DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg Product Name Phthalimidinoglutarimide-propargyl-C2-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-C2-OH

SKU 33203510676
4.4
USD445.00 USD494.00

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Ships within 48 hours · Estimated delivery Aug 24 - Aug 29

Description

Product Name Phthalimidinoglutarimide-propargyl-C2-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-C2-OH CAS Number 2138441-30-0 Related CAS Molecular Formula C18H18N2O4 Molecular Weight 326

Cy3-CA CAS Number Related CAS Molecular Formula C40H57ClN3O3 Molecular Weight 663

382 SMILES OC(=O)CCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

3-triazole linkages

DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg Product Name Phthalimidinoglutarimide-propargyl-C2-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-C2-OHSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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