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DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) chelator making it a powerful tool

SKU 32096347035
4.2
EUR245.00 EUR287.00

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Description

making it a powerful tool for monitoring SARM1 activation in biochemical assays

Beyond monitoring protein aggregation

Product Name DOTA-C4-amine Synonyms CAS Number 753421-63-5 Related CAS Molecular Formula C20H38N6O7 Molecular Weight 474

Product Name 4-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}butanoic acid Synonyms CAS Number 1240619-81-1 Related CAS Molecular Formula C13H24N2O4 Molecular Weight 272

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) chelator making it a powerful toolSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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