Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB Size:50mg CC(C)(C)C(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCCN=[N]#N)C1=CC=C(OC(=O)C(C)(C)C)C=C1O2 Purity (HPLC): ≥ 95%

CC(C)(C)C(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCCN=[N]#N)C1=CC=C(OC(=O)C(C)(C)C)C=C1O2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia

Product Name Thalidomide-O-PEG6-propargyl Synonyms Thalidomide-4'-O-PEG6-propargyl CAS Number n/a Related CAS Molecular Formula C28H36N2O11 Molecular Weight 576

1038/s41467-023-44237-4

Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB Size:50mg CC(C)(C)C(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCCN=[N]#N)C1=CC=C(OC(=O)C(C)(C)C)C=C1O2 Purity (HPLC): ≥ 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as