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Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:25mg 438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)

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Description

438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

387 SMILES OCCOCCOCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DBCO-Propionyl-Val-Cit-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C58H82N8O16 Molecular Weight 1147

far-red fluorescence

Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:25mg 438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a

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