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Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-Exatecan Size:5mg Product Name: 5(6)-ROX azide Synonyms:

SKU 26328716862
4.9
USD445.00 USD491.00

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Description

Product Name: 5(6)-ROX azide Synonyms: 5-(and -6)-Carboxy-X-rhodamine Azide CAS Number: N/A Molecular Formula: C36H36N6O4 Molecular Weight: 616

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

Product Name Thalidomide-C7-Br Synonyms Thalidomide-4'-C7-Br CAS Number n/a Related CAS Molecular Formula C20H23BrN2O4 Molecular Weight 435

21 Purity (HPLC) >= 95% Solubility DMSO

Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-Exatecan Size:5mg Product Name: 5(6)-ROX azide Synonyms:SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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