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Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan AHPC 253 Purity (HPLC) >= 95%

SKU 20561425843
4.5
USD445.00 USD472.00

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Description

253 Purity (HPLC) >= 95% Solubility DMSO

highlighting its strong affinity and potential as a precision tool in targeted protein degradation studies

62 SMILES Cl

Product Name Lenalidomide-C4-acid Synonyms Lenalidomide-4'-C4-acid CAS Number 2338824-29-4 Related CAS Molecular Formula C18H21N3O5 Molecular Weight 359

Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan AHPC 253 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent

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