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TMX-4100 can be used for the research of multiple myeloma
Product Name Phthalimidinoglutarimide-C4-Br Synonyms Phthalimidinoglutarimide-4'-C4-Br CAS Number n/a Related CAS Molecular Formula C17H19BrN2O3 Molecular Weight 379
Sci Transl Med 2021
SulfoCy5-CA CAS Number Related CAS Molecular Formula C43H60ClN3O9S2 Molecular Weight 862
Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) Size:50mg TMX-4100 can be used forSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker
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