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O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCN3CCNCC3)C=CC=C12 Purity (HPLC): 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only
S)-AHPC-CO-C2-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C29H44Cl2N6O4S Molecular Weight 643
491 Purity (HPLC) >= 95% Solubility DMSO
NCCCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCN3CCNCC3)C=CC=C12 Purity (HPLC): 95% ShippingSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers
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