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Datasheet MSDS
Product Name Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C76H106FN9O24 Molecular Weight 1548
NCCOCCOCCOCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name Phthalimidinoglutarimide-propargyl-C3-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-C3-OH CAS Number 2413731-69-6 Related CAS Molecular Formula C19H20N2O4 Molecular Weight 340
Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg Datasheet MSDSSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly
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